• High quality and reproducible data
    • assay controls continuously tracked and included in each assay
  • Rapid turnaround time
  • Flexible assay formats, protocols and reporting templates
  • Assay packages tailored to meet project requirement


Flexible In Vitro ADME study designs
Physicochemical Profiling                                                            
  • Intravenous, Oral
  • Subcutanous, intaperitoneal, intramuscular,intradermal, topical
  • Intranasal, intratracheal
  • Intracolonic
Permeability and Transporters
  • Serial sampling

Tail-vein,saphenous vein

  • Cathether(jugular,femoral)
  • Heart puncture (terminal)
 In Vitro Binding assays
  • Whole blood,plasma,serum
  • Tissues/organs
  • Excreta (urine,feces)
  • Cerebrospinal fluid (rat)
  In Vitro Metabolism and Drug-Drug Interaction
  • Metabolic stability

Microsomes, S9, Hepatocytes, Recombinant enzymes

Stability in plasma, blood and biorelevant media

  • Extrahepatic Metabolism

Intestinal microsomes and homogenates

  • Non-CYP Mediated Metabolism

Aldehyde Oxidase Reaction Phenotyping

  • Metabolite Identification and Interspecies profiling
  • Reactive Metabolite screening (GSH)
  • DDI

Cytochrome P450 inhibition and MDI using liver microsomes or recombinant CYP enzymes


For further details on the ADME/PK services available at Fidelta, please follow the indicated links or contact us.