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- 3D Structure of Macrocycles»
- Challenging Macrolide Chemistry»
- Crystal Structure and Physicochemical Properties of the Crystalline Form of a Novel 15-membered Azalide Derivative»
- Fragmentation Study to Facilitate Structural Elucidation of Novel Macrocycles»
- Forced Degradation Study»
- Impurities, Degradants and Metabolites in Three Steps»
- Initial Scale–up and Process Improvements for the Preparation of a Lead Antibacterial Macrolone Compound»
- Interactions between Macromolecules and their Ligands in Solution State»
- Isolation of Low Level Impurity»
- Novel Desosamine-Modified 14- and 15-membered Macrolides without Antibacterial Activity»
- Novel Macrolide Antibiotics»
- Preparation of Heterocyclic Synthons for Dibenzo[e,h]azulenes»
- Physicochemical Profiling of Macrocycles»
- Fragment NMR Screen on BRD4»
- Solid and Solution Stability and Solubility of a Crystalline Form of a Novel 15-membered Azalide Derivative»
- Triple Reuptake Inhibitors (TRUI) Project»
- Understanding Solid State Behaviour Hot Stage Microscopy»
- In Vitro Pharmacology»
- Assays on Clinical Samples»
- Biochemical Screening»
- Biofilm Studies on Pseudomonas Aeruginosa»
- Ca2+ - Flux Inhibition Fluorescence Assay in Jurkat Cells»
- Cellular Pharmacokinetics»
- Cytotoxicity / Proliferation Screening»
- Drug Interaction with ABC Transporters»
- Enzyme Kinetics»
- Ex Vivo Immunophenotypization»
- Functional In vitro Assays»
- Human Differentiated Leukocyte Assays»
- Human Primary Leukocyte Assays»
- Microbiology»
- In Vivo Pharmacology»
- Bleomycin Induced Pulmonary fibrosis in mice»
- Airway hyperresponsiveness (AHR) in ovalbumin induced asthma in BALB/c mice»
- Acute COPD exacerbation in mice with Influenza A virus (Puerto Rico/8/1934(H1N1))»
- Mouse model of infection induced by Influenza A virus (Puerto Rico/8/1934(H1N1))»
- 11-day Tobacco Smoke Induced Pulmonary Neutrophilia In Mice»
- Acute Tobacco Smoke Induced Pulmonary Neutrophilia In Mice»
- Cantharidin Induced Inflammation In Mice»
- Chronic DSS Induced Colitis in Mice»
- CIA in Mice and Rats»
- Croton Oil Induced Ear Edema in Rats»
- KLH Induced Delayed Type Hypersensitivity in Rat»
- KLH Induced Delayed Type Hypersensitivity in Mice»
- LPS Induced Bone Resorption in Mice»
- LPS Induced Pulmonary Neutrophilia in Mice»
- LPS Induced Septic Shock in Mice»
- LPS Induced TNF-a Production in Mice»
- Mouse Anti-CD3 Induced Inflammation»
- Mouse Model of Allergic Asthma»
- Mouse Pneumonia Induced by Intranasal Infection with ESBL Producing Klebsiella Pneumoniae»
- Mouse Pneumonia Induced by Intranasal S. Pneumoniae / H. Influenzae Infection»
- Mouse Sepsis Model Induced by IP Infection with K. Pneumoniae, P. Aeruginosa and S. Aureus»
- Oxazolone Induced Acute Delayed Type Hypersensitivity (DTH) in Mice»
- Oxazolone Induced Chronic Delayed Type Hypersensitivity (DTH) In Mice»
- PMA Induced Ear Edema in Mice»
- Thigh Infection Model in Healthy and Neutropenic Mice Induced by ESBL Producing Klebsiella Pneumoniae»
- Wound Healing Model - Excisional Wound»
- Xenograft (A549) Tumor Model»
- ADME / PK»
- Bioanalysis»
- Blood Partitioning»
- Cytochrome P450 Inhibition in Human Liver Microsomes»
- DDI CYP Inhibition Using Recombinant Enzymes»
- DDI CYP450 MDI in HLM»
- Metabolic Stability Hepatocytes»
- Metabolic Stability Microsomes»
- Permeability Caco-2»
- Permeability MDCK Wild Type»
- Permeability MDCKII-MDR1»
- Plasma Protein Binding»
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- 2nd Anglo-Croatian Medicinal Symposium on Macrocycles Medicinal Chemistry and Beyond-the-Rule-of-Five / October 17-18, 2016 / Fidelta, Zagreb, Croatia»
- Adrijana Vinter appointed new Managing Director of Fidelta»
- Mirjana Bukvic named the 2017 Young Medicinal Chemist in Industry»
- Around the macrolide – Impact of 3D structure of macrocycles on lipophilicity and cellular accumulation»
- Events»
- 6th RSC-BMCS FRAGMENT-BASED DRUG DISCOVERY MEETING - Vienna, Austria - March 5-7, 2017»
- NMR Pharma Day - Zagreb, Croatia - April 4, 2017»
- ATS 2017, May 19 - May 24, Washington, DC»
- 1st RSC Anglo-Nordic Medicinal Chemistry Symposium 11 - 14 June 2017, Copenhagen, Denmark»
- 14th European ISSX Meeting, 26-29 June 2017, Gürzenich, Cologne, Germany»
- 10th Joint Meeting on Medicinal Chemistry 28-28 June 2017, Dubrovnik, Croatia»
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