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Mouse model of infection induced by Influenza A virus (Puerto Rico/8/1934(H1N1))

BALB/c mice are orally treated with Ribavirin for 5 days, starting 4 hours prior to infection with PR8 (H1N1) via intranasal inoculation.

Read-outs:

  • survival rate
  • viral load in lung tissue
  • concentration of cytokines in lung tissue

 

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