Scaling up key molecules can revolutionise the way you do chemistry for the project. For example, with one key intermediate you can increase the chemist’s productivity multi-fold, consequently boosting the whole decision making process. And if speed is not the only thing you need, we can provide:
Synthesis of an advanced intermediate that will accelerate your process
Large scale synthesis of an advanced intermediate
Large scale synthesis of standards and building blocks
Larger compound quantities for in vivo studies
And any other request from milligram to multigram scale
The scale-up team is a group of well-educated and highly experienced organic chemists, medicinal chemists and chemical engineers that can offer solutions to your requirements in a quick and efficient manner. Our non-GMP scale-up laboratory is equipped with:
- Five double-jacketed glass reactors (2, 5, 10 and 20 L)
- Hydrogenation autoclave (4 L)
- 10 L and 20 L rotary evaporators
- Four highly precise and powerful thermostats.
We are able to perform various reactions within a wide temperature range (from -70 °C to 150 °C) and under different pressures (small scale to 100 bar, large scale to 10 bar).
The scale-up laboratory is well supported by the internal discovery analytical services, structural analysis, as well as the solid state characterization capabilities.
The improvement of your synthetic route is our challenge – to maintain the product’s high quality, while making the route:
- Cheaper – increase yields, shorten the reaction time, improve work-up
- Greener – decrease waste generation, reduce number of solvents
- Safer – compliant to the highest safety and environmental regulations
Reproducible and robust
By choosing Fidelta’s scale-up team, you will ensure good protection of your intellectual property through our rigorous data integrity policy. After completing the task, each compound can be accompanied by either a detailed research report or Certificate of Analysis
, both written in English.